• A longitudinal study of objective dating app usage and its relation to mental health in adolescents.
    4 months ago
    The use of dating apps among adolescents is a growing public concern. Past research, which almost exclusively relies on self-reported dating app usage, highlights an increased risk of victimization, but also opportunities to develop personal and social identity, particularly for minoritized youth. Thus, the present study used a mobile sensing app that passively tracked dating app usage over 6 months in 149 adolescents with a wide range of internalizing disorder severity. Thirty-five (23.5%) adolescents used dating apps across the 6 months (indexed by any keyboard input across dating apps), averaging 1.74 (SD = 1.12, range = 1-6) apps per person. At baseline, users (vs. nonusers) were older, more pubertally mature, and more likely to identify as sexual and gender minorities. Controlling for differences in demographic characteristics using propensity score matching, users and nonusers were largely comparable in clinical characteristics, with only a few differences evident: (a) greater self-reported frequency of risky behaviors at baseline and (b) greater number of weeks meeting major depressive disorder criteria across the follow-up period. Exploratory, within-person analyses in a subset of 18 users showed that a greater number of messages sent in dating apps was associated with a greater likelihood of having (subthreshold) depression symptoms in the concurrent week. Importantly, these findings are cross-sectional, and therefore the causal direction of effects remains unclear. Overall, passive monitoring of dating behaviors affords a unique lens on socioemotional development in youth, revealing nuanced relations between dating app usage and mental health among adolescents. (PsycInfo Database Record (c) 2025 APA, all rights reserved).
    Mental Health
    Care/Management
  • The child and adolescent trauma screen self- and caregiver-report: Factor structure, measurement invariance, and concurrent validity in a clinical sample of children and adolescents.
    4 months ago
    The child and adolescent trauma screen (CATS) is a widely used tool for assessing posttraumatic stress symptoms in youth; yet very few studies have examined its factor structure, including its measurement invariance and validity, across relevant groups. This information is critical to ensure evidence-based use of the measure while minimizing the risk of inaccurate interpretation.

    Utilizing a sample of 259 youth, aged 8-16 years (M = 11.7, SD = 2.4; 63% female), and their caregivers, the factor structure of the CATS was examined, and the optimal factor structure was tested for measurement invariance and construct validity across relevant groups.

    A three-factor structure based on International Classification of Diseases 11th Revision criteria for posttraumatic stress disorder that includes "reexperiencing," "avoidance," and "perceived sense of threat" factors based on six items from the total scale was identified as optimal for both CATS self- and caregiver-report (self: χ² = 7.514, root-mean-square error of approximation = .032, comparative fit index = .995, Tucker-Lewis index = .988, standardized root-mean-square residual = .024; caregiver: χ² = 9.663, root-mean-square error of approximation = .049, comparative fit index = .989, Tucker-Lewis index = .971, standardized root-mean-square residual = .032). In addition, measurement invariance was found for this three-factor structure for CATS self-report across youth age, sex, and race. In addition, concurrent validity was found for the CATS self-report total score, as evidenced by significant positive associations with self-reported depression symptoms.

    These findings support the use of the total score based on the six-item three-symptom version of the CATS that is based on International Classification of Diseases 11th Revision criteria for posttraumatic stress disorder. Further, these results provide some of the first replicable support for this three-factor structure of the CATS and suggest its use as a highly efficient, short-form screener that may be administered easily across clinical settings. (PsycInfo Database Record (c) 2025 APA, all rights reserved).
    Mental Health
    Care/Management
  • Multivariate Base Rates of Standard- and Skyline-Cutoff Elevations on the Personality Assessment Inventory: Do They Distinguish Simulated from Genuine PTSD?
    4 months ago
    Multivariate base rates (MBR) of elevations are an emerging psychometric paradigm for enhanced interpretation of multiscale self-report data. The aims of this study were to calculate and compare MBR of scale/subscale elevations on the Personality Assessment Inventory (PAI) and determine the ability of MBR to differentiate between mood disorders (n = 524, k = 3), military-based posttraumatic stress disorder (PTSD; n = 252, k = 2), and coached PTSD-simulator (n = 160, k = 1) groups. Overall, having at least one standard (T ≥ 70) and skyline elevation on clinical scales and clinical subscales was common across the groups. However, differential abnormal elevation thresholds emerged for each group. For instance, it was unusual (i.e., MBR < 10%) for the mood disorders group to have ≥ 1 (9.7%) and for the genuine PTSD group to have ≥ 3 (9.1%) skyline-elevated clinical scales. For subscales, it was unusual for the mood and PTSD groups to have ≥ 3 (7.6%) and ≥ 7 (8.3%) skyline-elevated clinical subscales, respectively. Conversely, PTSD simulators commonly yielded profiles with standard- and skyline elevations on nearly all clinical scales and subscales. MBR cutoffs identified from receiver-operating characteristic curve analyses yielded robust sensitivity (.650-.806) and specificity (.833-.984) in differentiating genuine PTSD and mood disorder groups from PTSD simulators. MBR are useful in differentiating genuine from simulated psychopathology, consistent with broader scale-based infrequency approaches.
    Mental Health
    Care/Management
  • Experiences/needs of US first responders, family caregivers, and children after TBI/catastrophic injury.
    4 months ago
    First responders (law enforcement officers, firefighters, and emergency medical personnel) are at high risk for traumatic brain injury (TBI) and other catastrophic injury (CI) requiring long-term caregiver support. The aim of this pilot survey was to investigate, via caregiver perception, the lived experiences and needs of: (1) US first responders who experienced TBI/CI, (2) the caregivers themselves, and (3) children living in the home.

    Caregiver participants (n = 27) completed an online survey including closed and open-ended questions.

    Results show first responders are living with adverse injury outcomes. Caregivers reported first responder suicidal ideation, suicide completion among their children, and a need for suicide risk support services. Four themes of most concern emerged. First responders are experiencing: (1) multiple challenges post injury (e.g., medical, benefits, vocational); (2) lack of support (e.g., state, departmental, peer, honor); (3) multiple adverse family impacts (e.g., relationship issues, family health); and (4) unmet/ongoing needs (e.g., education, alternative treatments, social support).

    The results provide critical data on US first responders with TBI/CI, their caregivers, and children. Study results can assist in the development of evidence-based supports and interventions to meet the needs of this understudied and underserved population.
    Mental Health
    Care/Management
  • Embracing the Modern Biochemistry of Brain Metabolism.
    4 months ago
    This editorial challenges the long-held neuron-centered view of brain metabolism, relying on ample evidence that it is a cooperative, multicellular process. Astrocytes, oligodendrocytes, and other glia play active roles providing lactate, antioxidant support, and substrate shuttles that fuel neuronal function and memory. Despite mounting data, some critics persist in refuting intercellular metabolic exchange, often guided more by entrenched creeds than concrete evidence, slowing constructive, hypothesis-driven discourse and delaying clinical and neuroprotective advances. The authors call for a rigorous research agenda: cell-type-specific manipulations, advanced biosensors, imaging and biomarkers, and integration with behavior and electrophysiology. They urge redirecting focus from outdated dogma to physiology-driven exploration of glia-neuron metabolic partnerships.
    Mental Health
    Care/Management
  • Emotion Regulation and Executive Functions in Insomnia Disorder Comorbid With Mood and Sedative-Hypnotic Use Disorders: Findings From a Naturalistic Longitudinal Study Employing Daridorexant in the Management of Chronic Insomnia.
    4 months ago
    Insomnia disorder has a considerable effect on mental health, making its effective management crucial in clinical practice. An observational study was conducted on consecutive outpatients with insomnia disorder (DSM-5-TR criteria) attending the Insomnia Clinic of the Psychiatric Unit of the University Hospital of Pisa (Italy). Patients were treated according to insomnia guidelines with DORA Daridorexant. Evaluations were performed at baseline (T0), 1 month (T1) and 3 months (T2). Data collected included clinical assessments of insomnia severity (Insomnia Severity Index [ISI]), depressive and mixed symptoms (Beck Depression Inventory II [BDI-II], Young Mania Rating Scale [YMRS]) and emotional dysregulation (Difficulties in Emotion Regulation Scale [DERS], Frontal Assessment Battery [FAB]). Concurrent pharmacological treatments were collected. The study included 90 patients (mean age 53 ± 13.6 years, n° = 43 females). A significant proportion (63.3%) was comorbid with unipolar or bipolar depression and sedative-hypnotic use disorders. Repeated measures ANOVA analyses revealed a significant improvement for the ISI, DERS and FAB over time, with F-values of 24.23, 15.56 and 21.74 (p < 0.001). Additionally, BDI-II and YMRS scores showed significant decreases during the same period, with F-values of 10.24, 10.33 and 70.00 (p < 0.001). Multiple regression analyses indicated that improvements in depressive symptoms were best predicted by improvement in DERS and ISI, while mixed symptoms were predicted by ISI and FAB improvements. With the caution of a naturalistic design, this study may show that by treating insomnia comorbid to other mental disorders, it may be possible to improve not only insomnia symptoms but also emotion regulation and executive functions.
    Mental Health
    Care/Management
    Policy
  • Work stress and its association with suicidal ideation, health and presenteeism during the COVID-19 pandemic: cross-sectional study in the UK health and university workforce.
    4 months ago
    Work stress levels rose among health and educational workforces during the COVID-19 pandemic, and can affect employee well-being and organisational efficiency.

    To explore the association of work stress with mental health, including suicidal ideation and physical health, as well as presenteeism, as aspects of organisational efficiency in UK healthcare and university workers.

    A total of 328 UK participants completed self-report questionnaires between April 2022 and September 2023 in the context of the European Platform to Promote Wellbeing and Health in the Workplace (EMPOWER) study. Cross-sectional analyses were conducted.

    Two hundred and ninety-two (90%) employees reported work-related stress (Mini-Psychosocial Stressors at Work Scale). Depressive, anxiety and somatic symptoms were reported (61, 55 and 75%, respectively); 11% of the participants reported suicidal ideation (Patient Health Questionnaire 9) and 56% reported presenteeism (iMTA Productivity Cost Questionnaire). Psychological and somatic symptoms were worse when suicidal ideation or presenteeism was reported. Stressful work factors included having too much work to do (63%), a bad working atmosphere (28%), poor work-home balance (32%) and working hours hindering private life (35%). Spearman correlations showed significant associations between work stress and suicidal ideation (0.225), depressive (0.290), anxiety (0.299) and somatic symptoms (0.245) and presenteeism (0.311), but not with having a chronic medical condition.

    Given the association between work stress, suicidal ideation and presenteeism, research should explore how psychosocial risk factors linked to work stress could be reduced for healthcare and higher education employees. The findings warrant the development of policies to address work stress, and to provide employee support for suicidal ideation and presenteeism in the work setting.
    Mental Health
    Care/Management
  • Cost-utility analysis of adjunctive psychosocial therapies in bipolar disorder.
    4 months ago
    There are few economic evaluations of adjunctive psychosocial therapies for bipolar disorder.

    Estimate the cost-utility of in-person psychosocial therapies for adults with bipolar disorder added to treatment as usual (TAU), from an Australian Government perspective.

    We developed an economic model, estimating costs in 2021 Australian dollars (A$) and outcomes using quality-adjusted life-years (QALYs) gained and disability-adjusted life-years (DALYs) averted. The model compared psychoeducation, brief psychoeducation, carer psychoeducation, cognitive-behavioural therapy (CBT) and family therapy when added to TAU (i.e. pharmacotherapy) over a year for adults (18-65 years) with bipolar disorder. The relative risk of relapse was sourced from two network meta-analyses and applied to the depressive phase in the base case. Probabilistic sensitivity analysis and one-way sensitivity analyses were conducted, assessing robustness of results.

    Carer psychoeducation was preferred in the base case when the willingness-to-pay (WTP) threshold is below A$1000 per QALY gained and A$1500 per DALY averted. Brief psychoeducation was preferred when WTP is between A$1000 and A$300 000 per QALY gained and A$1500 and A$450 000 per DALY averted. Family therapy was only preferred at WTP thresholds above A$300 000 per QALY gained or A$450 000 per DALY averted. In sensitivity analyses, brief psychoeducation was the preferred therapy. Psychoeducation and CBT were dominated (more costly and less effective) in base-case and sensitivity analyses.

    Carer and brief psychoeducation were found to be the most cost-effective psychosocial therapies, supporting use as adjunctive treatments for adults with bipolar disorder and their families in Australia.
    Mental Health
    Care/Management
  • Lived and care experiences of chronic musculoskeletal shoulder pain in Australian adults: A qualitative study.
    4 months ago
    Australian evidence on lived and care experiences of chronic musculoskeletal shoulder pain (CMSP), irrespective of disorder classification or disease, is limited. However, such evidence is important for person-centred care and informing local service pathways and care guidelines or standards. To address this gap, we explored i) lived experiences of adults with CMSP across domains of the International Classification of Function, Disability and Health (ICF) Framework, and ii) their care experiences, preferences and priorities for CMSP.

    A qualitative study, applying a phenomenological approach and purposive sampling was conducted with adults experiencing CMSP. Individual semi-structured interviews, informed by ICF domains, explored lived and care experiences/preferences of participants. Data were analysed using an inductive approach, by objective.

    Twenty adults (50% women) with diverse CMSP conditions/diagnoses, clinical profiles and age (21-76 years) participated. Five lived experience themes were identified: 1) impact on body functioning; 2) impact on sleep, energy and drive; 3) impact on mental well-being and evolving sense of self; 4) coping with CMSP; and 5) social support and participation. Four care experience themes included: 1) care seeking choices; 2) interactions with healthcare professionals (HCPs); and 3) values and preferences for components of CMSP care.

    Adults with CMSP experience impacts across life stages in multiple domains of functioning (ICF categories) relating to personal and social dimensions. Clinical encounters, particularly interactions with HCPs, influence an individual's confidence and engagement in their care. Discussion, education and goal setting through shared decision-making are valued attributes of clinical encounters among people with CMSP.
    Mental Health
    Care/Management