Effectiveness of digital healthcare to improve clinical outcomes in discharged patients with coronary artery disease.
Post-discharge management of coronary artery disease (CAD) remains clinically challenging, with digital healthcare's efficacy underexplored. This study analyzed 16,797 CAD patients enrolled in the HeartMed Digital Management System (June 2018-September 2022), comparing outcomes between a digital management (DM, n = 4,713) and conventional management (CM, n = 12,084) cohort over 12 months. Cox models adjusted for confounders revealed significantly reduced all-cause mortality in the DM group (1.6% vs. 2.7%; HR 0.58, 95% CI 0.45-0.75, p < 0.001) and lower risks for major adverse cardiovascular events (MACCE: 6.4% vs. 9.2%; HR 0.67, 0.59-0.77, p < 0.001), cardiovascular death (HR 0.70, 0.51-0.95), myocardial infarction (HR 0.38, 0.29-0.50), recurrent angina (HR 0.75, 0.65-0.87), revascularization (HR 0.84, 0.71-0.99), and readmissions (HR 0.76, 0.68-0.84) (p < 0.05 for all). Digital healthcare demonstrates superior post-discharge optimization of CAD outcomes, significantly attenuating mortality and morbidity.